Tracer Determinations of Human Red Cell Membrane Permeability to Small Nonelectrolytes
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منابع مشابه
Tracer Determinations of Human Red Cell Membrane Permeability to Small Nonelectrolytes
A flow system has been used to determine the permeability of human red cell membranes to four small nonelectrolytes labeled with (14)C. The permeability coefficients, omega, in units of mol dyne(-1) sec(-1) x 10(15), are: ethylene glycol, 6; urea, 13; formamide, 22; and methanol, 131. The values for urea and formamide are in good agreement with values obtained by Sha'afi, Gary-Bobo, and Solomon...
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The permeability of human red cell membrane to 90 different molecules has been measured. These solutes cover a wide spectrum of nonelectrolytes with varying chemical structure, chain length, lipid solubility, chemical reactive group, ability to form hydrogen bonds, and other properties. In general, the present study suggests that the permeability of red cell membrane to a large solute is determ...
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VARGAS, FERNANDO, AND JOHN A. JOHNSON, Permeability of rabbit heart capillaries to nonelectrolytes. Am. J. Physiol. 2 r 3(1> : 87-93. 1967. -Isolated perfused rabbit hearts were used to study the permeability characteristics of their capillaries with respect to inulin, raffinose, sucrose, and urea, The method used involved a continuous weighing of the isolated perfused heart. Each heart was iso...
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The endothelial surface of the isolated rabbit cornea was perfused with modified KEI medium, according to the method reported previously. This in vitro cornea maintained its thickness within the normal range even after the epithelium ivas removed. The endothelial permeability of these in vitro corneas to tritiated water, >C-labeled urea, sucrose, and inulin teas determined. The reflection coeff...
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The permeability coefficients of dog red cell membrane to tritiated water and to a series of[(14)C]amides have been deduced from bulk diffusion measurements through a "tissue" composed of packed red cells. Red cells were packed by centrifugation inside polyethylene tubing. The red cell column was pulsed at one end with radiolabeled solute and diffusion was allowed to proceed for several hours. ...
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ژورنال
عنوان ژورنال: Journal of General Physiology
سال: 1971
ISSN: 1540-7748,0022-1295
DOI: 10.1085/jgp.58.3.259